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Antimicrobial, antivirotic and antimycotic solgel applicable as a nanolayer to various surfaces

 CZECH REPUBLIC Technology collaboration OFFER Created: 18/05/2015
Last updated: 07/08/2015
Fecha límite: 06/08/2016
Resumen

Czech university has developed and patented solgel used for creation of a nanolayer that has provable antimicrobial , antivirotic and antimycotic effects. The nanolayer is applied to diverse surfaces (glass, metals, ceramic, textile, some plastics) and has a good chemical and mechanical resistance. Applicable in hygiene-demanding places (health and social care, food industry). The university looks for a license agreement with a producer capable to manufacture the solgel.

Descripción completa

Currently used disinfectants (chlorine, steam, etc.) show only temporary antibacterial activity while, some of them, have a negative effect on the environment. Apart from this, the novel solution has antibacterial, antivirotic and antimycotic effects that last for about 1 year.

A Czech university has developed a special solgel that is applicable to various materials like glass, metals, ceramic, textile and some plastics. The solgel is applied in a form of nanolayer the thickness of which ranges from 80nm to 300nm. As soon as the solgel is applied, it is further polymerized by heat and photochemical reactions

The sol, used for creation of the nanolayer is an organic-anorganic polymer solution that changes its form to gel. Thin gel nanolayer, ranging from is 80nm up to 300nm, is created and it is fixed to the treated surface by way of thermal polymerization or photo-polymerization. Resulting surface has provable antibacterial, antivirotic and antimycotic effects whether or not the treated material is exposed to daylight or darkness.

When treated surfaces are exposed to UV A, the effectiveness of the nanolayer notably increases and during tens of minutes the surfaces are practically free of viruses and bacteria.

Actually, nanolayer works on the principle of synergic effect among Ag, Cu and Zn elements that are incorporated in a form of cations with ion bonds to anorganic part of hybrid polymer.

The cations have bacteriostatic effect owing to their ability to penetrate biologic membrane of a bacterium where they affect proteosynthesis process and DNA replication.

The technology of application of the nanolayer is very effective and complex form of antibacterial, antivirotic and antimycotic protections that lasts for about 1 year.

The university has done several tests of selected applications (e.g. disposable medical products).

The university looks for a license agreement with a producer capable to manufacture the solgel.

Socio buscado:

- Specific area of activity of the partner: The university looks for a license agreement with a producer capable to manufacture the solgel.

Advantages & innovations:

Provable effect of the nanolayer against pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Acinetobacter baumanii, Pseudomonas aeruginosa)

Provable antivirotic effect (HIV, Dengue)

Provable antimykotic effect (Candida albicans, Candida glabrata).

Tests of cytotoxicity showed to be negative (VERO and HeLa cells)

Nanolayer´s thickness: 80nm up to 300nm, 150nm on average

Very good mechanical resistance (wear away tests showed good resistance during pressure of 750g per 5000 cycles

Very good chemical resistance against toluol, acetone, diluted acids (sulphuric acid, nitric acid, hydrochloric acid).

Very good adhesion to substrates like glass, metals, ceramic, textile and most plastics

Long-term resistance of treated textile (50 cycles of washing)

Resistance during repeated sterilization process (120 °C / 1 hour)

Antibacterial effects do not depend on whether a treated object is exposed to light or darkness.

Simple application – the solgel is applied as a nanolayer by spraying and/or immersion

Development Stage:

Field tested/evaluated

IPR:

Patent(s) applied for but not yet granted - Patent applied in the Czech Republic

Clasificado como: Manufactura Industrial Alimentación y bebidas Acuicultura y Pesquería    Pesca Industria

» Reference: TOCZ20150507001

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This project has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [605658].

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