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UK-based university seeks companies with expertise in medical device development to help produce protoype diagnostic device

Biomarkers are a powerful tool in medical diagnostics. However many of them require labels in order to be detected or otherwise require detection methods that reduce the possibility of integration into a compact and portable biosensor setup. This limits their use especially in point of care diagnostics.

A UK university has developed a heat transfer method of detection. This has enabled them to develop a thermal detection platform technology that has the potential to overcome this liability and produce a flexible, point of care diagnostic device.

This thermal detection platform technology is based on analysing the heat-transfer resistance of a functionalized solid?liquid interface in time. Changes in thermal resistance caused by the presence of different molecules gives the output reading. This thermal detection platform technology has been combined with various synthetic and natural receptors for various applications including the detection of whole cells and microorganisms, neurotransmitters and hormones, and proteins using surface imprinted polymers (SIPs), molecularly imprinted polymers (MIPs), and aptamers, respectively.

The UK university is looking to further develop this platform from a bench-top proof of concept model to a prototype device. They are looking for industrial partners with experience and expertise in the development and prototyping of medical devices, especially diagnostic devices, to help them with this process. It is envisaged that this partnership will take the form of a research cooperation agreement or a technical cooperation agreement.

» Reference: TRUK20170731002/UNITED KINGDOM

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This project has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [605658].

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